<b>Introduction:</b> The Post COVID Functional Status Scale (PCFS) was designed to measure functional changes in patients after SARS-COV2 infection. <b>Objective:</b> To compare the status of fatigue, dyspnea, and mental health of patients with COVID-19 according to the PCFS score. <b>Methods:</b> Cross-sectional study that included patients hospitalized for at least 10 days. Were grouped according to the PCFS score. In addition, the Fatigue Assessment Scale (FAS), Hospital Anxiety and Depression Scale (HADS), and the modified Medical Research Council (mMRC) were applied. The study was approved by the ethics committee of Clinica de Occidente in Cali-Colombia. <b>Results:</b> Between February and August 2021, 72 participants (age 57.4 +/− 15.3 years, 47,2% women) were included; patients with a score of 3 and 4 in PCFS presented worse levels in the result of FAS, HADS, and mMRC (p < 0.001) compared to the other groups; participants with a score of 0 had better results in the clinical variables (Table 1). <b>Conclusion:</b> Patients with COVID19 with greater functional limitations also have more impact on fatigue, dyspnea, anxiety, and depression; this result stimulates the referral of patients to rehabilitation programs.
