The analysis of potential fluid flow is possible using different techniques of structural geology. This work utilizes stress tensors inversion and quantification of fracture patterns along a mesa landform, with results that contribute to the conceptual hydrogeological model of Mesa de Los Santos, in the Eastern Cordillera of Colombia. The area was subdivided into three blocks separated by the NW Potreros and Los Santos faults, with minor faults of different orientations in their interior. This separation facilitates the analysis of the fractures measured in the field, which in general show high inclination angles and a conjugate geometry in the northern block and tension (Mode I) in the central block, while the distribution is random in the southwestern block. Win-Tensor treatment of slickensides yielded a SHmax of 111º which coincides with the NWW-SEE tensor observed from the conjugate and tension joints. The use of FracPaQ allows us to verify this stress tensor in most of the Rose diagrams from outcrops and connectivity ellipses suggesting transit in this NWW-SEE direction. The interpolation of fracture intensity and density values shows the central block with the highest values, while the lowest values are located in the northern one, where there is more precipitation that causes the greater weathering of the rock and homogenization of the fracture planes. Although the highest values of connectivity by line are found to the south of the mesa, good possibilities of flow from the recharge zone are suggested along bedding planes and open NW-SE fractures.