Functional class (FC) is a useful tool for decisions in hypertension pulmonary management. Regulatory bodies in Colombia require a high FC to authorize prescriptions. However, the usefulness of FC should be verified in the Colombian Andean zone. <b>Objective:</b> To analyze the functional class (NYHA CF) from referenced centers in Colombian Pulmonary Hypertension Network. <b>Methods:</b> A cross-sectional study in 7 health centers. We included patients with PVR>3Wu and used Kruskal Wallis and Pearson's Chi2 and Spearman's correlation tests for evaluating differences and correlations between FC, PVR and pulmonary pressures. <b>Results:</b> 245 subjects (45%) show a weak correlation between FC and PVR (Rho= 0.1865) and about 45% of FC-I present PVR ≥10Wu. Despite of significant differences between CF and sPAP (p=0.0265), the correlation is moderate (Rho= 0.1544) (Table 2). On heat map, we founded discordance in 7% of patients with a FC-I and high PVR/pulmonary pressures (Figure 1a-1b). <b>Conclusions:</b> Correlation between FC, PAP, and PVR is weak, generating a proportion of patients with FC does not agree with diagnosis parameters, thus limiting the treatment.
