A knee arthroscopy exploration is a minimally invasive surgical procedure; but training residents to perform it is complex and expensive. In addition, years of training are required to perform the procedure correctly and safely. An interactive Mixed Reality application was developed with the purpose of providing an alternative for the procedures training, which seeks to create a practice environment for training surgeons while promoting safe learning. Hololens 2 was used to project holograms of the procedure scenario, and a set of optitrack tracking cameras were placed to track the instruments and simulate the operation. In the design process, a CTA (cognitive task analysis) was carried out, which functions as a fundamental guide to establishing a step-by-step procedure and finding the most significant difficulties when executing it. In the interaction with the application, the user must complete several tasks and simulate an arthroscopic knee exploration procedure within a virtual scenario. Tests were conducted with medical students, general practitioners, and orthopedic experts to test the application's performance as an educational tool. The results showed that the application is a valuable tool to improve the learning of this type of procedure,providing a suitable practice environment for skill improvement.