Polarization singularities and topological polarization structures are generic features of inhomogeneous vector wave fields of any nature. However, their experimental studies mostly remain restricted to optical waves. Here, we report the observation of polarization singularities, topological Möbius-strip structures, and skyrmionic textures in 3D polarization fields of inhomogeneous sound waves. Our experiments are made in the ultrasonic domain using nonparaxial propagating fields generated by space-variant 2D acoustic sources. We also retrieve distributions of the 3D spin density in these fields. Our results open the avenue to investigations and applications of topological features and nontrivial 3D vector properties of structured sound waves.