Summary The Neves-Corvo mining area in southern Portugal has proven in the past decades to be a notable example for the use of seismic technologies for the detection and targeting of volcanogenic massive sulphide (VMS) deposits, in particular copper and zinc bearing Lombador and Semblana. Post-stack acoustic inversion was used having as input a 3D reflection seismic volume from the area together with sonic and density logs from a well intersecting the Semblana deposit. Resulting in a density attribute volume that matched the known Semblana deposit, and that also allowed to characterize the density body corresponding to the Lombador deposit. Additionally showing that a strong shallow reflection associated to a lithological contact did not represent a high-density feature, making a good case for the predictability of seismic inversion methods for mineral exploration in hardrock settings. This method would allow to predict and export a geobody of rock properties, in particular density, analogous to the VMS deposits in the Neves-Corvo area.