Music has a unique capacity to create a resonance through various sound practices that feed collective action. For this reason, it has become one of the most important repertoires within the different cultural tactics used for political and social mobilization. Within the framework of social protest, we seek here to understand the role of music as a key language in the grammars of resistance and social transformation, its functions, forms and affects. We will first examine the connection between art and politics, and then delve into the weave of sound that emerges during the protest, until we reach a reading of the experience of Segunda Línea, a group that arose in the midst of what is known as the social outbreak in Colombia.