Objective: It is stated that coronavirus disease-2019 (COVID-19) is mainly transmitted through cells expressing angiotensin converting enzyme 2 receptors. In our study, the relationship between oral hygiene habits and COVID-19 exposure of individuals during the COVID-19 pandemic period was studied. Material and Methods: After obtaining ethical approval of the study, individuals aged 20 and over who wanted to participate in the study were included. During the COVID-19 pandemic period, the questionnaire form examining the oral and dental health of the individuals was sent online between 01 and 10 January 2021. Survey form consisted of questions to measure demographic information (gender, age), status of having COVID-19, and oral hygiene habits. Analysis of the data in the study was done using the Pearson chi-square test (p0.05). Among the individuals participating in our study, 13.8% (n=90) of those who brushed their teeth 2-3 times a day, 20.4% (n=69) of those who brushed their teeth once a day, and 21.3% (n=16) of those who brushed 2-3 times a week had COVID-19. Individuals using mouthwash (12.1%; n=57) had less COVID-19 compared to individuals who had not use mouthwash (19.1%; n=118). It was found that 33.6% (n=358) of individuals increased the frequency of tooth brushing during the COVID-19 pandemic period. Conclusion: In our study, it was observed that individuals who used regular tooth brushing and mouthwash during the COVID-19 pandemic had less COVID-19 disease. Therefore, it is considered that raising awareness about individual measures to protect oral and dental health will be useful in preventing COVID-19 transmission.