A 2^3 factorial design was performed to analyze the performance of a mini-split air conditioningsystem under several psychrometric air conditions at the evaporator inlet, similar to tropical regionconditions. In addition, a search for new energy-saving opportunities was performed. The resultsshowed that interactions between the temperature of the air inlet, humidity of air inlet, and fanspeed level are significant in the mini-split energy performance under tropical climate conditions.Hence, it is necessary to work on an oriented energy savings control strategy. Therefore, this studyrecommends developing a fan speed control scheme, generating energy savings of around 10% in theair conditioning unit.