Using the Mathisson-Papapetrou-Dixon equations together with the Tulczyjew spin-supplementary condition, we study the circular orbits of a spinning test particle moving in the equatorial plane of a quantum improved Rotating Black Hole (RBH) spacetime. This background metric incorporates a position-dependent gravitational constant $G(r)$ and its behavior determines the quantum corrections to the properties of the Innermost Stable Circular Orbit (ISCO). The obtained results show that the radius of the event horizon as well as the radius of the ISCO for the quantum improved RBH are smaller than those of the Schwarzschild or Kerr solutions.