Many phenotypes have been described in the literature, the most named being the post-COVID 19 neurological syndrome, due to the findings of SARS-Cov-2 neurotropism and the process of active or passive neuroinflammation that can be generated during the acute phase of this disease, even in the absence of neurological symptoms. 3onsidering that the nervous system is very susceptible to injury and slow and unsafe recovery, it is one of the most serious phenotypes of attention. 3Older patients with comorbidities have a higher risk of developing the severe COVID-19 phenotype, and in these patients, neuroplasticity is reduced due to age and microvascular injury from vascular enlargement and atherosclerosis. 3This leads us to think about the need to follow up on the neurological integrity of all patients who undergo a definitive diagnosis of COVID-19.