Dear Editor, An association between primary hyperparathyroidism (pHPT) and the development of rheumatological diseases has been suggested. In some of these cases, the treatment of hyperparathyroidism led to the resolution of the autoimmune phenomena. In addition, our group has found that patients with SLE and primary SS (pSS) have increased expression of the hormone receptor (PTHR1) on B lymphocytes, positioning it as a possible helpful biomarker in SLE and disease activity marker in pSS [1]. Here, we aimed to describe the rheumatological diseases autoimmune rheumatic disorders (ARDs) and non-autoimmune rheumatic disorders (NARDs) in patients with pHPT. We conducted a retrospective study evaluating electronic clinical records of patients with pHPT referred to rheumatology between 2011 and 2021 in the University Hospital Fundación Valle del Lili (UHFVL). This tertiary health centre provides highly complex health services in Cali, Colombia, with a bed availability of >581 beds. This study complies with the declaration of Helsinki and the UHFVL’s Ethics Committee approved this study protocol (No. 1771).