To determine through the systematic review the survival rate of patients infected by SARS-CoV-2 and previously diagnosed with arterial hypertension and/or diabetes.A systematic review of the literature, in eight electronic and bibliographic databases, was conducted from July 8 to 21, 2020. Different combinations of the terms DECS and MESH were used as: ('SARS-CoV-2' OR 'COVID-19') AND ('diabetes' OR 'arterial hypertension') AND ('Survival rate' OR 'Prevalence rates'). The selected articles are retrospective, single-center or multi-center, observational cohort studies of patients with COVID-19 disease who had diabetes and/or arterial hypertension. These were subjected to risk of bias assessment, with the help of critical and methodological guidelines (STROBE) and level of evidence (CEBM).326 articles were analyzed by title and type of study, of which 20 were considered relevant. Finally, five retrospective cohort studies that met the inclusion criteria, made in Wuhan, China, were included in this review. All the selected studies affirm that diabetes and hypertension are related to a decrease in the survival rate in patients with COVID-19. Three studies with evidence level 2b and grade of recommendation B, mention factors related to an increase in the survival rate, these are: well-controlled blood glucose, which maintains glycemic variability within 70.26 to 180.16 mg/dL (3.9 to 10.0 mmol/L), patients on pre-admission antihypertensive therapy for SARS-CoV-2 and diabetic patients who do not require insulin may have a lower risk of disease progression and a better prognosis. Additionally, two articles with evidence level 2b and grade of recommendation B, mention the survival rates of 10.6 and 13.9% for diabetics, while 18.8 and 23.4% for hypertensive patients.Based on the evidence included in this review, until now, having comorbidities predisposes patients with COVID-19 to a lower probability of survival. It is recommended to consider that adequate glycemic control and blood pressure are guidelines that benefit the recovery of these patients. However, more studies are needed to identify possible preventive and therapeutic strategies for a more comprehensive management of these patients.