The work compiles the findings of an investigation focused on the structure of the medical tourism value chain in Bucaramanga-Colombia, characterizing the relationships between the actors that make it up and explaining the dynamics of the health cluster in Santander. It is a cross-sectional study with explanatory scope within the qualitative paradigm, which raises the need to integrate tourism with the health cluster as a mechanism to position this destination internationally, improving the economy of the region. key words: medical tourism, value chain, health cluster.