The main objective of this research was the design, construction and validation of a scale to measure the psychosocial factors and the organic symptomatology in the workplace. The study was non-experimental and crosssectional. It included a sample of 363 participants from three private companies and one from the government sector in Puerto Rico. The scale was submitted to a panel of ten expert judges in order to determine its content validity and, subsequently, it was administered to the sample. The construct validity of the scale was made by an analysis of factors, which determined the suitability of the dimensions and reagents. The development of the scale for measuring the psychosocial factors and their effect on the symptoms proves to be a useful tool as an early intervention strategy.