To identify and describe low-density lipoprotein cholesterol (LDL-C) levels in patients diagnosed with hypertension and diabetes in the Colombian health system in 2016. A descriptive, observational study of 299,770 patients over 18 years of age with a diagnosis of hypertension and diabetes mellitus reported by 48 insurers in 2016. 37% of the population between 60-69 years of age had altered levels of LDL-C with values between 160-189 and ≥190; While 1.3% of people aged 30-39 reported the lowest proportion. Almost 80% were classified as overweight or obese. Levels of high and very high LDL-C were more frequently found in people with sistolic blood pressure between 120 and 139 mmHg followed by the group between 120 mmHg and in a third position in the 140-159mmHg group. High levels of LDL-C were identified in 9% of the population with hypertension and diabetes. It was determined that the increase in body mass index is related to LDL levels; for 7 years, these patients have been monitored through prevention programs, which must be focused on the management of the disease and evaluation of indicators that show the management of the insurers in the care processes.