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Glucose and inulin: Caenorhabditis elegans a model of diabetes

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ID Minciencias: ART-0000464252-178
Ranking: ART-ART_A2

Abstract:

Carbohydrate levels in the diet are important in a wide variety of living organisms, due to essential requirements such as the production and use of energy to meet the basic demands of cellular functioning.However, the high supply of glucose carbohydrate is a risk factor in the development and maintenance of metabolic disorders such as diabetes; in addition, to be closely related to the excessive production of radioactive oxygen species (EROs), which generate loss of redox balance, direct cellular damage, involvement of the critical component of the aging process, initiation and development of diseases of notable morbidity and mortality (atherosclerosis, cancer, diseases of the central nervous system, autoimmune diseases, ischemia-reperfusion injury) among others.Caenorhabditis elegans is an adequate model in a wide variety of studies.Some studies suggest that the increase in glucose metabolism decreases the half-life of C. elegans, so it has become a model of studies of oxidative stress that can be produced in diabetes mellitus.

Tópico:

Genetics, Aging, and Longevity in Model Organisms

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Información de la Fuente:

FuenteMOJ Bioorganic & Organic Chemistry
Cuartil año de publicaciónNo disponible
Volumen2
Issue2
PáginasNo disponible
pISSNNo disponible
ISSN2574-819X

Enlaces e Identificadores:

Minciencias IDART-0000464252-178Scienti ID0000464252-178Open_access URLhttps://medcraveonline.com/MOJBOC/MOJBOC-02-00057.pdf
Openalex URLhttps://openalex.org/W4242129152Doi URLhttps://doi.org/10.15406/mojboc.2018.02.0057
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