Abstract:
Pharmacological effects -in vitro/in vivo evaluations Results 0.5-5 mg/kg/b.w., 29-41% red.(hind paw edema mice model) F-RF: 2.5 mg/kg, red.30% leukocytes and 90% leukotriene B4; EE: 75% leukotr.B4 25 mg/kg, 52% inh.# writh.(ind.acetic acid); 50 mg/kg, 60-90 min, antinociception 300 mg/kg, 30% urine decr.(rats) 2 mg/kg, 65% red.urinary peroxides (CP-ind.acute renal lesions in rats) 50 mg/kg, 65% inh.(writhing test) Artemia salina, IC 50 : 48-895 mg/L
Tópico:
Botanical Research and Chemistry