Type 2 diabetes is considered a public health problem mainly affecting women, that combined with poor adherence to therapeutic treatment and poor sleep quality increase this health problem. To determine existing associations between sleep quality, adherence to therapeutic treatment and HbA1c levels in women with T2D from a community in Puebla. A cross-sectional descriptive correlational study was conducted using a sample calculated at 0.05 level of significance, 0.30 correlation coefficient and 90% statistical power to obtain n=110. Instruments used were personal data forms, Pittsburgh Sleep Quality Index (PSQI), Martín-Bayarre-Grau (MBG) Questionnaire to assess therapeutic adherence and Eclipse A1c analyzer. A negative significant relationship was found for sleep quality with HbA1c levels (rs=-.355; p=.001), but not for the treatment adherence treatment variable. Retrieved data is in accordance with other studies reaffirming indirectly all biochemical reactions occurring during sleep deprivation. Findings herein contribute to the strengthening of the scientific side of nursing oriented to care improvement, which will serve for the design of interventions promoting healthcare in women with type 2 diabetes.