A humane and respectful treatment of patients by the staff has inspired the creation of the Department of Humanism and Bioethics at the University Hospital of Fundación Santa Fe de Bogotá which not only has met, but even surpassed established goals. Since 2013, the Department has developed different activities that have made it possible to respond more ethically to the daily needs of patients and to strengthen other humanization processes. Currently, the Department of Humanism and Bioethics addresses five lines of work: a continuing education program, an assistance advisory program, support, and strengthening of existing committees, support for the activities of our institutional humanization program and research activities. This article updates the experience of this Department, specifically focusing on notable changes in the last years.