Background: Ophthalmia nodosa (ON) was first described by Schön in 1861, and since then it has received multiple names, broadening the identification of the causal agents.In Colombia there are no precise references to these agents.Objective: To perform a review of an underdiagnosed entity such us ON.Material and methods: To report of five patients diagnosed with ON in Clinica Barraquer, Bogotá, Colombia from January 1983 to December 2020.Retrospective and narrative literature analysis.Results: Patients presented complete resolution once the described treatment was carried out on time.Conclusions: ON is a well-known disease that requires a high clinical suspicion to be diagnosed.Topical corticosteroids are the first line of treatment and removal of the foreign body is recommended.