This article analyzes the behavior of the Free Trade Agreement signed between Colombia and the Northern Triangle countries. It is based on the hypothesis that, because there is an agreement between countries of the South, similar global development conditions reduce the asymmetries in terms of trade, characteristics of North-South agreements. To evaluate the hypothesis, this article analyzed the trade flows of the last ten years (2010 – 2019), and different international trade indicators are estimated. The results indicate that the agreement has been favorable for Colombia, generating a surplus trade balance and an increase in exports of products with high added value and complementarity between trade partners. It is suggested to deepen and expand this agreement and promote its use by the national productive apparatus.