Polycyclic aromatic hydrocarbons (PAHs) are organic compounds widely distributed in the environment that are associated with adverse health effects, they are constituted as atmospheric pollutants mainly caused by combustion processes. The temporal dynamics of PAHs were determined during the daily cycle, through samplings in two stations located in Medellín, one urban with a mesoscale trend (MED-EXSA) and another urban background (MED-ITMR) during March, June and October 2019 at through measurements in real time with a PAS 2000 photoelectric sensor and with analysis of 16 priority PAHs by gas chromatography mass spectrometry in PM10 samples taken in 12-hour periods simultaneously. The results obtained showed a bimodal behavior in the concentrations of PAHs, with maximum values evidenced near 6:00 (peak 1) and at 18:00 (peak 2), which coincide with the periods of greatest vehicular traffic. Likewise, there were significant differences (p <0.05) of the average values between the evaluated periods and between the sites, possibly associated with the differences in vehicle flows and the prevention measures established by the environmental authority. The concentrations of the 16 PAHs evaluated in PM10 were between 37 and 121 ng.m-3, with Dibenzo [ah] anthracene being the one with the highest incidence, not finding significant differences (p> 0.05) between the 12-hour periods evaluated. Comparison with the PAS 2000 sensor responses showed a good correlation (r> 0.5) for the MED-ITMR station data. The cancer risk estimated from the concentrations found was between 9x10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-5</sup> and 1x10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> , which constitutes an important risk, higher than the reference value recommended by the American Environmental Protection Agency.