The purpose of this case report is to share a new clinical colonization of a zoonosis condition. This is the case of a 39-year-old female patient who presented to the Emergency Department with a Paragonimus colonization of oral cavity after consumption of raw crab. This article shows the lab works and clinical challenges that Oral and Maxillo-Facial Surgery Department had to overcome to successfully treat this patient and clearly demonstrates that complete medical record continues to be a fundamental tool for correct targeting towards the diagnosis and treatment of any pathological entity.