Dengue is the viral disease transmitted by arthropods that causes the most morbidity and mortality worldwide.In today's world, this arbovirus is considered the tenth cause of death, especially in pediatric ages.The infection can be asymptomatic or express with a wide clinical spectrum that includes severe and non-severe expressions.The most severe manifestations, previously called dengue hemorrhagic fever and dengue shock syndrome, occur in less than 5% of cases.With the recognition of the severe forms of dengue, the disease has received great global attention and is today considered the most important viral hemorrhagic disease.Thanks to the fact that some national and international studies have reported that the unusual manifestations of dengue hemorrhagic fever are relatively frequent and are associated with a higher mortality rate on the recognition of severe forms of dengue, the disease has received great worldwide attention and is now considered the most important viral hemorrhagic disease.