<i>Introduction</i>: Prostate cancer (PC) is the second most frequently diagnosed tumor in men, and bone scan (BS) is one of the diagnostic images used for staging and follow-up. Precise indications for performing a BS exist and an overuse of this diagnostic modality is suspected. It is relevant to evaluate the medical pertinence when requesting a BS to promote self-regulation, protect the health system and reduce radiation doses. <i>Methods</i>: This is a descriptive, retrospective study. Medical records of patients with PC diagnosis were reviewed. We included patients evaluated by a urologic oncologist at the outpatient scenario, at San Ignacio Hospital, Bogotá, Colombia, in the second trimester of 2019. Epidemiological and staging data were recorded for each patient, as well as the number of BS requested, the type of BS performed, the PSA at the time of performance and the impact of the result on medical decisions. Clinical indications for requesting a BS were classified, according to RADAR III guidelines. An analysis was performed using Excel (measures of central tendency and frequency). <i>Results</i>: A total of 234 patients were evaluated (mean age: 74.47 years; mean follow-up time: 32.3 months). At least one BS was requested in 55% of patients (mean 1.54), with a total of 199 BS performed. The most frequent indication for a BS was PSA progression in patients with androgen deprivation therapy (ADT), in hormone-sensitive prostate cancer (31%). 18% of the requested BS could have been omitted (inappropriate indication). The mean PSA at performance for BS that showed bone metastasis (33%) was 151.27ng/ml and 19.75ng/ml for those negative (67%). Medical behavior was not impacted by the result of any of the BS that didn´t have an appropriate indication according to the established guidelines, but it was affected by 85% of those correctly requested. <i>Discussion and Conclusions</i>: BS is a conventional image that it widely performed for the staging and follow-up of PC. There are precise indications according to the NCCN and RADAR III guidelines for performing one in a PC patient. It was observed that with some frequency it is requested unnecessarily, without having any impact on the clinical decisions for the patient. The relevance of medical self-regulation and knowledge of scientific evidence are highlighted to prevent unnecessary exposure to radiation, optimize the impact of the results of these tests on clinical behavior and protect the health system.