Background: Cancer is a global problem. Estimates for 2018 expect around 18.1 million new cases and 9.6 related deaths worldwide. Interestingly, there is significant geographical variation in cancer research that has an inverse correlation with cancer-specific mortality. In Latin America (LATAM), the percentage of gross domestic product (GDP) invested in research is below 1% in the majority of countries. The region has been a participant in only 4.6% of clinical trials in cancer worldwide and produced only 4% of all scientific publications. Methods: This study, a bibliometric analysis of cancer-related publications in LATAM establishes the relationship between sociodemographic factors and countries, taking into account authors and their networking efforts. We implemented a high sensitivity search strategy for cancer publications between 2000 and 2018 using the Scopus database, limited to LATAM nations. We constructed collaboration networks for both authors and citations for LATAM and each country in the region, calculated correlations between the number of included publications, author and national indicators. Findings: The search included 8528 articles across 9 countries. Brazil was the most productive nation with 41.8% of the included references. Mexico (16.6%), Argentina (12.9%), and Chile (9.7%) followed. LATAM experienced a 9% growth in publications. Peru had the greatest percentage growth (23%). Number of publications by country highly correlated with author network size (r = 0.75, p = 0.019). Percentage of invested GDP in research and development correlated positively with the number of publications for most nations.Interpretation: LATAM has experienced a significant growth in cancer related publications. Furthermore, it highlights the importance of scientific networking as a strategy for increasing scientific productivity. Hopefully, these results will serve to bolster oncology related publications in the region, further contributing with cancer research and leading to progress in the scientific field. Funding Statement: This study was self-funded.Declaration of Interests: The authors declare no potential conflict of interest related to this article. Ethics Approval Statement: Due to the nature of the study, no approval of an institutional Ethics and Research board was required.