The expansion of urban areas and the growth of the urban population are challenges faced by different territorial administrations across the world. In this context, the objective of this document is to analyze land occupation and the distribution of land uses in Bogotá and 17 municipalities. Therefore, a methodology is proposed in which an accessibility indicator models the spatial structure of the territory based on employment concentrations (the sum of the number of jobs weighted by the distance between each pair of municipalities). Then, the analysis of land use is carried out using a multinomial model, with the accessibility indicator as its principal explanatory variable. In such a way, it is possible to estimate the effects associated with the location decisions of economic agents in the territory. The results will enable policy makers to identify location and relocation patterns; we found evidence of a greater probability of commercial uses within urban areas and a relocation of industrial activity towards rural areas in some municipalities.