The formulation of public policy regarding comprehensive sex education in Argentina has been the subject of contests and disputes between different positions. In this article, we will approach from a socio-semiotic perspective the relationships between the different discursive positions that were locked in the formulation processes of this public policy in the educational field. The enactment of the Law that obliges the educational system throughout the country to implement comprehensive sex education in schools is part of a historically settled field of disputes involving discursive formations related to biomedicine, human rights, religion and movements feminists. The socio-semiotic analysis that we propose allows us to genealogically investigate such power relations and point out opacities and gaps in the formal production of this public policy that operate as conditions of confrontations that remain in force.