Retinoblastomas are the most common primary intraocular malignancy of childhood, with a high incidence in the first 2 years of life. This is the report of the first unilateral retinoblastoma case in a 57-year-old Colombian female, who presented to consultation with an advanced neovascular glaucoma in the left eye. Examination revealed an amelanotic intraocular mass that required enucleation. The histopathology report and specific tumor markers of the enucleated specimen revealed the diagnosis. A 10-year follow-up was carried out with [...]