We report for the first time the greenhouse frog Eleutherodactylus planirostris from San Andrés, the largest Colombian Caribbean island. This record represents the second known frog species on the island, and the second invasive Eleutherodactylus species reported from Colombian territory. In addition, we describe and discuss the morphology and some aspects of the natural history of this newly documented and well-established population. Additional research about the ecological impacts of invasion of E. planirostris on natural ecosystems and native species of San Andrés are required.