Asthma is the most common chronic lower respiratory disease in childhood throughout the world; it is characterized by bronchial hyperreactivity and variable airway obstruction. Asthma is a disorder involving autonomic nervous system, immunologic, and psychologic factors in individuals. This work sought to describe the relationship among stress, coping, and disease control in children with asthma between 6 and 12 years of age. This was a cross-sectional correlational quantitative study with the participation of 280 children with asthma admitted to outpatient consultation and to a hospitalization service at a tier IV health institution in the city of Bogotá. An inverse correlation was found between stress and coping (