The conceptualization of the notions of sustainable habitat, integrative design and complexity raises the need to address the questions, how to contribute to the habitat sustainable from transdisciplinary processes? What is the responsibility of design in the current context? Moreover, how to face the complexity of thinking and responding to the urban, architectural and technological phenomena? These approximations are built from three perspectives: cultural and comprehensive management of the territory; technology, environment and sustainability; and integrative design, habitat and project. For this, it begins with a reflection on the meaning of design in relation to way, and how this is understood as a meta-discipline that integrates the voice of experts with that of people who live, enjoy or suffer from design objects. Subsequently, the relation between the notions of integrative design, habitat and complexity, in light of transdisciplinarityFrom this framework, it deepens the link among governance, resilience and urban reconversion, in times of neoliberal and hypercompetitive globalization, based on ecological ethics, civic participation and co- responsibility. On another scale, the connection among technology, environment and sustainability, from a vision of the future based on the use of energy; resource consumption; waste recycling, among others. As closure, addresses the matter of project research from an epistemological reflection that compromises the relationship between processes, maps and territories, to establish strategic notes for research-creation. As a conclusion, the commitment to reflection and the exercise of a responsible and integrative design.