The southern Goiás state region of Central Brazil has an extensive and informative record of fossil biota. Particularly over the last five years, there has been a great increase in fossil finds, which has enabled a greater understanding of this region's fauna and flora during the Late Cretaceous. In this article, we provide an updated synthesis of the biota from the Cretaceous of the southern Goiás state, the record of plants, gastropods, turtles, crocodilians, titanosaurs, and theropod dinosaurs.