espanolIntroduccion: la gestacion es un periodo de importantes cambios fisiologicos, morfologicos y psicologicos que a su vez se asocian con la calidad de vida relacionada con la salud (CVRS). Objetivo general: describir las publicaciones sobre CVRS de gestantes en el periodo 2008-2019 y analizar sus dimensiones en salud fisica y mental con el SF-36. Materiales y metodos: revision sistematica en MedLine-Pubmed, Scielo y Google Scholar. Se garantizo exhaustividad, reproducibilidad y calidad metodologica. Se estimo la media de salud fisica y mental del SF-36 con su intervalo de confianza del 95% mediante un meta-analisis de efectos aleatorios. Resultados: se identificaron 21.683 investigaciones de las cuales 63 cumplieron el protocolo e incluyeron 32.107 gestantes. Los estudios aplicaron 20 escalas de CVRS siendo mas frecuente el uso del SF-36, SF-12 y WHOQOLBREF. Los estudios analizaron el perfil de CVRS de la gestante y su relacion con otras variables como depresion, ansiedad, estres, calidad del sueno, actividad fisica, salud oral, diabetes e HTA. En 17 estudios con 7.849 gestantes sanas que aplicaron el SF-36 o SF-12, el puntaje de CVRS en el componente fisico fue 52,7 (IC95%=52,4-53,0) y el mental 54,1 (IC95%=53,8-54,4). Conclusion: los estudios sobre CVRS en gestantes se concentran en pocos paises, con estudios que exploran su correlacion con comorbilidades o sintomatologias de salud mental. Se dispone de multiples escalas siendo mas utilizada la SF-36, segun esta escala la gestacion afecta la CVRS tanto en el componente fisico como en el mental. EnglishIntroduction: Gestation is a period of important physiological, morphological, and psychological changes that in turn are associated with health-related quality of life (HRQOL). Objective: To describe the publications on HRQL of pregnant women in the period 2008-2018 and analyze their physical and mental health dimensions with the SF-36. Materials and methods: A systematic review in MedLine- Pubmed, Scielo, and Google Scholar was conducted. Dimension, reproducibility, and methodological quality were guaranteed. The mean SF-36 physical and mental health was estimated with a 95% confidence interval using a random effects model. Results: A total of 21,683 investigations were identified, of which 63 complied with the protocol and included 32,107 pregnant women. The studies applied 20 HRQL scales, and the use of SF-36, SF- 12, and WHOQOL-BREF was more frequent. The studies analyzed the HRQL profile of the pregnant woman and its relationship with other variables such as depression, anxiety, stress, sleep quality, physical activity, oral health, diabetes, and AHT. In 17 studies with 7,849 healthy pregnant women who applied the SF-36 or SF-12, the HRQL score in the physical component was 52.7 (95% CI = 52.4–53.0) and 54.1 (IC95 % = 53.8–54.4) in the mental component. Conclusion: HRQL studies on pregnant women are concentrated on few countries, these being studies that explore their correlation with comorbidities or mental health symptoms. Multiple scales are available, the SF-36 being the most used, according to this scale, pregnancy affects HRQL in both the physical and mental components.