The objective of the present investigation is to identify the level of prevalence of Burnout syndrome and the relationship with the sociodemographic characteristics in primary and secondary teachers in the Eje Cafetero, Colombia. The methodology is quantitative, cross-sectional, exploratory. To identify the prevalence, the Burnout Maslacsh Inventory was used, as well as a sociodemographic survey was used to identify the particularities of the teachers. A random sampling with a confidence level of 95% and a margin of error of 3% was used, the sample consisted of 352 primary and secondary teachers from the public and private sectors. The results show a low prevalence in teachers of Burnout syndrome. A greater illness in men, in young teachers, in teachers with less than one year of service and secondary school teachers. It is concluded that in Colombia teachers have a low prevalence of the syndrome, qualitative studies are required to indicate the causes of the disease.