The aim of this article was to explore the dimensions of quality of life related to health and academic satisfaction of university students. The methodology used was quantitative, observational, cross-sectional, prospective, descriptive and correlational. The compilation of the information was carried out through a battery made up of two scales; a) the SF-12 questionnaire and the Academic Satisfaction scale. The sample consisted of 467 students, the sampling method that was used was non-probabilistic, through the convenience sampling strategy. The statistical techniques that were used were descriptive and correlational statistics. The contribution of the study lies in the statistical empirical evidence that allows affirming that the dimensions of physical role, emotional role and vitality favor the academic satisfaction of university students. If students feel comfortable with their school atmosphere, enjoy their school activities, and are enthusiastic about their majors, they will have better physical and mental health.