Introduction: Spinal cord injury (SCI) is any type of spinal cord neural injury that can result in sensory, motor deficits, autonomic and sphincter dysfunction, below the level of the lesion.Objective: To know the functional profile of patients with SCI and its relationship with different etiologies.Methodology: Cross-sectional observational study, carried out at CRER.Epidemiological questionnaire, Core Set of SCI of the International Classification of Functionality, Disability and Health (ICF) and Spinal Cord Independence Measure (SCIM III) were applied.Results: sample of 65 patients with SCI, traumatic etiology predominating (74.2%), male gender (69.7%), mean age 37.75 (± 15.14) years, paraplegia level (53.1%) and AIS A lesions (38.5%) (p <0.05).Non-traumatic injuries have a better functional prognosis.Sphincter control and locomotion have worse functionality.Conclusion: there is a predominance of traumatic, paraplegic, complete injuries in young adult male individuals, with a predominance of sphincter dysfunctions, muscle strength and locomotion.