Introduction:Osteoarthrosis of the knee is a degenerative disease that affects the quality of life of people, in professional soccer players repetitive physical activity may be related to this pathology.Therefore, this research aims to evaluate the findings by magnetic resonance associated with the degenerative changes of the knee of professional soccer players. Materials and Methods:Retrospective analytical observational study of cases and controls with a 1: 3 ratios of probabilistic sampling to determine the development of knee osteoarthrosis in professional soccer players using frequency table analysis, central tendency measures and secondary analysis Chi2, Fisher, T student.Results: a total of 260 patients were included for the analysis with a mean age of 56 years, weight of 71 kg, with moderate physical intensity and long exposure to physical activity, the prevalence of osteoarthritis in soccer players was 80%.The most important changes are meniscal extrusion, alteration of the anterior cruciate and medial collateral ligaments, as well as intra-articular joint effusion. Conclusion:the profession of professional soccer player increases the risk of developing osteoarthritis with significant magnetic resonance alterations that show joint effusion, meniscal extrusion and ligament alteration of the anterior cruciate and medial collateral.