In the present clinical and observational study we have analyzed sixteen patients with type II diabetes, ranging from 56 to 88 years-old., and showing blood hypertension (84%) %), cardiovascular diseases (43%), memory disorder (43%), Parkinson disease (31%), Headaches (25%),. Sleep disorders (18%), gait disturbances (18%), language disorders (18%), dizziness and vertigo (12%), cervicogenic headache (12%) liver diseases (12%), gastrointestinal disease (12%) arthritis (12%), respiratory diseases (6%), Alzheimer disease (6%), and previous cerebrovascular accident (6%). We have diagnosed six mixed syndromes of diabetes and Parkinson disease (37%), three patients with diabetes and Alzheimer disease (18%) two cases with diabetes, blood hypertension and Alzheimer disease (12%) and two case with diabetes and cervicogenic headaches (12%). The pathophysiological mechanisms involved are described in each case. A relationship of diabetic patient lifestyle with environmental conditions, low socioeconomic status and family history is postulated.