The most important issues that affect consumer fruit acceptance in the ‘Hass’ avocado international market are flesh disorders. These defects can be influenced by both pre- and postharvest factors. The aim of this work was to evaluate the effect of the harvest season, storage time, mineral content, and preharvest variables on internal fruit disorders. Here, fruit was sampled from four farms in Antioquia (Colombia) at 22%, 26%, and 30% dry matter (DM) content. Samples were stored and ripened under simulated export conditions. Then, flesh bruising, flesh discoloration, body rots, vascular browning, stem end rot, and mineral content were assessed. The results showed that flesh disorders differ among farms and by harvest index and storage time. The most frequent defects found were vascular browning and stem end rot. Boron, calcium, nitrogen, manganese, magnesium, and potassium have a strong relationship with flesh disorders. Therefore, high boron and calcium contents, as well as a harvest at 26% DM, can substantially reduce avocado flesh disorders and improve internal fruit quality. Farmers that had a high flesh and soil mineral content and low rainfall and temperature produced fruits with fewer internal disorders.