Aims & Objectives: Adopting medical technologies like ECMO marks a region’s progression indevelopment. The number of ELSO-registered and unregistered ECMO centers in Latin America (LA) has increased rapidly. 1916 LA cases have been filed in the ELSO registry, with an unknown number of cases performed at unregistered centers. Reported survival rates are comparable to those in the international registry. This growth has driven an increased need in training new ECMO teams. Tailored educational resources are scarse. Methods: Our annually conducted courses are 3.5 days long. Lecturers are Spanish-speaking international multidisciplinary ECMO experts who work in different environments. Participants are novice multidisciplinary health care providers, working/starting new ECMO programs. Courses are based on didactic lectures, practice based learning (PBL) and simulation (SIM) activities. Learning objectives, PBL and SIM cases, and debriefing techniques are tailored to each ECMO team’s level of expertise and type of practice. Courses cost less than $450 per person. Sustainability of acquired knowledge is the responsibility of each new program, however, after the course, the main lecturers provide continuous support to the new teams, in real time, using multiple media options. Results: The overall evaluation of all courses is >4.7/5 (Likert), for all aspects evaluated. Results on the impact of having all Spanish-speaking instructors, knowledge of the environment/culture, post-course continuous support and course’s cost/value evaluations will be provided. Conclusions: Training of new ECMO teams should be tailored to learners and practice. International multidisciplinary teams of expert ECMO instructors familiar with the learners’ culture, language and at minimal cost, results in successful new ECMO programs.