Aims & Objectives: Children with complex congenital heart disease after the first palliative procedure, especially in Hypoplastic Left Heart Syndrome (HLHS) have a high rate of morbidity and mortality during the period they remain at home until the second intervention. The analysis of the outpatient period outcomes of our institution was performed. Methods: Retrospective review of clinical records of the Heart Institute of Floridablanca, 4th level center, between 2015- 2018 was performed. All newborns with HLHS or another congenital heart disease that required a palliative surgical or interventional procedure to acquire clinical stability to be discharged, were included. Clinical characteristics were analyzed. Results: 178 total outpatients, six (3%) died and 66(37%) were lost during outpatient follow-up, without any difference between univentricular and Biventricular pathways (37.4%vs37,2%, p:0.98). 106 patients were alive at the end of outpatient period. 75%(80) were candidates to second procedure and only 76 patients had intervention, four of them are still on ambulatory setting. There was not a significant difference in mortality for univentricular and biventricular pathways (6.5%vs4,1%, p:0.69). The Follow-up was similar in both groups (CI95%=-86,46; p:0.10) with a median of 271 days (IQ165-391). Conclusions: The outpatient period for newborns and infants in this cohort implies a high number of losses in the outpatient follow-up and a similar mortality regardless the expected pathway. Factors influencing the high amount of follow-up losses and management require further studies and the development of novel strategies.