This research analyzes the governance and administration of the Colombian district and national government, regarding the migratory and refugee crisis, within the framework of COVID-19. Based on clinical work and regulatory provisions, from the concept of invisibility, as well as the governance of migrations with a differential approach, it was examined the district and national government’s capacity to manage solutions facing COVID-19, towards population in need for international protection. Thus, in the face of late and inefficient responses, the absence of a differential approach that perpetuates the invisibility of the migratory crisis and of refugees in pandemic was evident.