Magnesium alloys have an excellent strength-to-weight ratio and can be manufactured with a lower environmental impact. Although its application is attractive for wheelchair design, it is little explored. As a result of this work, an all-terrain wheelchair was designed, exhibiting a weight reduction of 32% compared to commercial products. Users performed usability tests, to evaluate the improvements achieved. This wheelchair can contribute to improving their quality of life, allowing users to save energy and preserve the health of their upper limbs. Finally, an impact was achieved in the local industry, developing capacities to manufacture products in these alloys.