Introduction: Autistic Spectrum Disorder - ASD is a deficit in behavioral neurodevelopment, directly and indirectly affecting social interaction and limiting the individual's actions. Objective: To assess the degree of knowledge of nursing students about Autism Spectrum Disorder. Materials and methods: it is an integrative literature review in the virtual databases: Latin American and Caribbean Literature in Health Sciences (LILACS), Scientific Eletronic Library Online (SCIELO) and Google Scholar, government sites, Results: 8 were selected articles published between 2010 and 2020, it was identified that the prevalence of cases of ASD has been increasing, due to the implementation of new diagnostic research tools. There is a great deficit in the nursing gadget about the theory and practice of this knowledge. Conclusion: the student's knowledge of Autism Spectrum Disorder at graduation will be decisive in the resolutive applicability of a better prognosis and effectiveness in therapeutic treatment. It is suggested to approach the TEA in nursing graduation in more detail both in theory and in practice, because, with the increase in the prevalence of the disorder, the future professional should have more security in his actions contributing to a quality of care.