Compartment Syndrome is defined as the elevation of tissue pressure above 30 mmHg in a compartment and because comparing the compartment tissue pressure with the diastolic blood pressure below 30 mmHg has proved to be more reliable, this is now a predecessor of Crush Syndrome, which is defined as a post traumatic rhabdomyolysis with systemic distress mainly associated with acute renal failure. The use of amputation as a method to improve the patient’s clinical condition is still controversial, thereby we present the clinical case of a patient rescued from a collapsed building 24 hours after the earthquake that affected Mexico City on September 19, 2017, followed by an updated literature review. Key words: Compartimental; crush syndrome; earthquake; amputation; trauma.