An integrated sustainability indicator in specialized dairy index (IISLE) is proposed for the evaluation of these production systems in four dimensions (financial, technical, social, and environmental). This index was validated in a study carried out with information from 18 dairy farms in Antioquia, a Colombian milk production region. The analytic hierarchy process (AHP) method was applied to prioritize criteria and sub-criteria. According to the proposed dimensions, four criteria were established (financial (ISDF), technical (ISDT), social (ISDS), and environmental (ISDA)) and 30 sub-criteria were analyzed. A multiple correlation analysis was performed to determine the intensity of the relationship among these four criteria and the overall index. The methodology includes a cluster analysis for the calculated IISLE. R software was used in the analysis. The proposed indicator is a powerful and useful planning and control tool for the evaluation of sustainability levels in dairy farms and is highly influenced by financial and technical criteria.