The inert Zee model is an extension of the Zee model for neutrino masses. This new model explains the dark matter relic abundance, generates a one-loop neutrino masses and forbids tree-level Higgs-mediated flavor changing neutral currents. Although the dark matter phenomenology of the model is similar to that of the inert doublet model, the presence of new vector-like fermions opens the lepton portal as a new dark matter annihilation channel. We study the impact of this new portal in the low-mass regime and show the parameter space allowed by direct and indirect searches of dark matter. Remarkably, the region for [Formula: see text] GeV is recovered for [Formula: see text]. We also show that future experiments like LZ and DARWIN could probe a large region of the parameter space of the model.