<b>Introduction:</b> COPD causes a progressive decrease in exercise tolerance and functional capacity. Pulmonary Rehabilitation (PR) has been endorsed as an effective treatment; however, strategies that further enhance the results obtained can be added to the PR; among them, Neuromuscular Electrical Stimulation (NEMS). The objective was to compare the changes that occurred in patients with COPD, before and after attending an 8-week RP program with and without the use of NEMS. <b>Methods:</b> Prospective interventional study; 20 patients were included in the PR group and 15 patients in the PR+NEMS group; who attended a PR program in Cali-Colombia for 8 weeks. The NEMS was added in quadriceps bilaterally during the performance of lower limb exercises in each session. <b>Results:</b> No were differences between the groups on the values at the beginning of the study. After 8 weeks, the 6-minute walk test distance (6MWT), the Modified Medical Research Council dyspnea scale and the repetition maximum test (RM), showed significant changes in both groups (p &lt;0.001). Regarding the intergroup comparision, We found that in the 6MWT and in RM, the changes obtained were greater (p&lt;0.05) in the PR+NEMS group (Figure 1). <b>Conclusions:</b> The addition of quadricipital NEMS during the training of pulmonary rehabilitation, generates greater changes in muscular strength and tolerance to effort in patients with COPD.